Surrounded by the Amazon army, the female body torture research facility faced imminent destruction. However, a researcher presumed dead returned with a newly developed, powerful aphrodisiac. Led by Tsuji Maru, the institute's forces resolved to rise again as the Insane Torture Research Institute and march into a new battle. Will the clash with the Amazon army prevent a repeat of past tragedies, or lead to the institute's total annihilation? Dominatrix Kanna unleashes a new form of herself, reaching the ultimate limits of pleasure through the newly developed aphrodisiac and unending torture.