Mako, a diligent medical student, witnesses a powerful professor sexually abusing his underlings. After this incident, she becomes his target and loses all means of self-defense, eventually being assaulted through despicable means. Though the professor deeply despises her, he demands crude and degrading sex from her. Repulsed and horrified, she is forcibly licked and raped. Unable to endure his escalating demands, she is coerced into sex while enduring it in a hospital room. In the midst of this humiliating experience, she is driven to orgasm against her will. The professor's utterly despicable sexual acts shake Mako's mind and body to the core.