Evil Clinic is a specialized facility that targets only big-breasted women. Patients are given a custom-blend drink laced with sleeping drugs, rendering them unconscious—after which their bodies can never return to normal life. Under the drug's effects, their minds and bodies come under complete control, with sensitivity to pleasure heightened to the extreme. Perverted men gather to torment the women's erogenous zones, drawing intense ecstasy from the core of their beings. Through this process, they experience overwhelming pleasure from just their nipples, eventually being swallowed completely by waves of orgasm.