Sadistic female researchers use male masochists as human test subjects for studies on detoxification effects. To examine how accumulated toxins and waste are expelled from the body, they force the subjects to consume large quantities of colored chemical drinks. They observe how these substances are excreted through sweat and urine, using incense, cigarettes, and lighters to burn the skin and induce sweating, exposing the penis to collect urine—and then making the subject drink his own urine. They violently whip the subjects, drip hot wax onto wounds and the penis, rub salt into the injuries to increase perspiration, and shove excess salt into their mouths. As demonstrations of detox, they force the subjects to urinate and defecate, then make them ingest their own excrement. Ruthlessly exploiting the male masochists, they lick and clean soiled body parts and anuses, pushing the human experiments to extreme limits.