Popular music teacher Remon Kirin, adored by her students at a music vocational school, visits a hospital one day and receives a mysterious medication from a doctor—only to discover it has unexpected side effects that will drastically alter the course of her life.
While the current economy struggles and most companies face hardship, one corporation continues to thrive. Having successfully developed a new product, they enlist maids to test it—a strangely captivating item that leaves everyone stunned.
Meanwhile, Dr. Sakura, a world-renowned expert in anal research, is deeply immersed in studying relaxation syndrome. His experiments soon draw in nurse Remon and maid Mitsuna as test subjects, thrusting them into an unimaginable series of events.