In a hospital examination room, a patient awaits treatment, but instead encounters two sadistic female doctors, BOTAN and RUIKO, who treat him like their personal toy. Sensing his masochistic tendencies, the two women begin subjecting his body to intense BDSM training under the guise of medical care. They force him to drink large amounts of enema solution, heightening his anal sensitivity until he easily accepts full fist insertion. His nipples, urethra, and anus are all pushed to extreme sensitivity, gradually transforming his body into that of a submissive female. This session in the examination room marks the first step toward his complete domination.